Key result
Inherited and acquired thrombophilia are linked to increased vascular pathologies and poor gestational outcomes.
Why the study?
Inherited and acquired thrombophilia are major causes of thrombosis in pregnant women and are associated with increased vascular pathologies leading to poor gestational outcomes.
This review highlights the association between thrombophilia and vascular placental pathology, discussing therapeutic modalities to improve gestational outcomes.
May support targeted screening in recurrent abortion; leaves open whether anticoagulation improves outcomes.
Inherited and acquired thrombophilia are the main cause of thrombosis in pregnant women. A growing number of reports over the last few years have suggested that these disorders are also associated with an increased incidence of vascular pathologies resulting in poor gestational outcome. This article discusses recent data concerning thrombophilia and vascular placental pathology, and discusses available therapeutic modalities to prevent placental vascular thrombosis and maximize successful gestational outcome.
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Benjamin Brenner (2005) conducted a review in Thrombophilia in pregnancy. Thrombophilia was evaluated. Inherited and acquired thrombophilia are associated with an increased incidence of vascular pathologies resulting in poor gestational outcomes, including abortion.
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