All articles of this category Aldehydes, converted in situ into N -(1-chloroalkyl)pyridinium chlorides using thionyl chloride and pyridine, react with 2-aminobenzyl-amine, under mild conditions, to yield 1,2,3, 4-tetrahydroquinazolines. The latter can be aromatized readily by treatment with 2,3-dichloro-5,6-dicyanobenzoquinone or tetrachloro-1,4-benzoquinone in benzene.
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Eynde et al. (1993) studied this question.