Key result
High SYNTAX score linked to ~292% higher in-hospital CV mortality risk versus low scores.
Why the study?
A high SYNTAX score is a known predictor of adverse outcomes in stable and unstable coronary syndromes, but its impact on in-hospital outcomes in STEMI patients undergoing primary PCI needed evaluation.
Does a high SYNTAX score predict in-hospital cardiovascular mortality in patients with STEMI undergoing primary PCI?
Population
646 STEMI patients undergoing primary PCI, mean age 56.1 ± 12.5, 516 males and 130 females
Comparison
High SYNTAX score (>21.75) vs low SYNTAX score (≤21.75)
Design
Prospective cohort study
Follow-up
In-hospital
Authors
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May flag higher-risk CAD patients for monitoring; leaves open prospective validation before routine use.
Cohort (n=646)
Does a high SYNTAX score predict in-hospital cardiovascular mortality in patients with STEMI undergoing primary PCI?
Odds Ratio: 3.92 (95% CI 1.1–13.9)
Absolute Event Rate: 10.7% vs 2.4%
p-value: p=0.03
A SYNTAX score >21.75 is an independent predictor of in-hospital cardiovascular mortality in STEMI patients undergoing primary PCI.
Kul et al. (2012) conducted a cohort in ST-elevation myocardial infarction (STEMI) (n=646). High SYNTAX score (>21.75) vs. Low SYNTAX score (≤21.75) was evaluated on In-hospital cardiovascular mortality (OR 3.92, 95% CI 1.1-13.9, p=0.03). A high SYNTAX score (>21.75) was associated with a significantly increased risk of in-hospital cardiovascular mortality compared to a low score (10.7% vs 2.4%; OR 3.92, 95% CI 1.1-13.9, P=0.03).
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