Key result
New CSC criteria reveal 90% of extreme high-risk ACS inpatients miss admission LDL-C targets.
Why the study?
The newly issued definition of extreme high-risk by the Chinese Society of Cardiology highlights expanding needs for lipid-lowering treatment in ACS patients.
What proportion of ACS inpatients meet the new CSC extreme high-risk definition and achieve LDL-C targets at admission?
Observational
What proportion of ACS inpatients meet the new CSC extreme high-risk definition and achieve LDL-C targets at admission?
A large majority of ACS patients are classified as extreme high-risk under new CSC guidelines, with significant gaps in achieving LDL-C targets, highlighting the need for more intensive lipid-lowering therapy.
Answers are grounded in this paper and cite their sources.
Large LDL-C gaps in extreme high-risk ACS inpatients; hypothesis-generating and requires prospective validation before informing care.
About three fourth of inpatients with ACS were categorized as extreme high-risk based on the new definition of CSC expert consensuses, nine out of ten patients at extreme high-risk didn't achieve the new LDL-C target at admission, and the intensity of lipid-lowering therapy was insufficient in clinical practice. There are substantially expanding needs for implementing more intensive and effective lipid-lowering strategies.
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Zeng et al. (2020) conducted an observational in Acute coronary syndrome. Extreme high-risk categorization (Chinese Society of Cardiology definition) was evaluated on Failure to achieve new LDL-C target at admission among extreme high-risk patients. Based on the new Chinese Society of Cardiology definition, 75% of ACS inpatients were extreme high-risk, and 90% of these patients failed to achieve the new LDL-C target at admission.
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