Genetic association study reveals an association with the ZNF91/LINC01224 locus in bilateral vestibulopathy, highlighting a novel etiology for unexplained inner ear dysfunction.
Bilateral vestibulopathy (BVP) is a chronic disorder resulting from bilateral loss of peripheral vestibular function. Although several etiologies have been identified, such as ototoxic exposure, bilateral Menière disease, and, more recently, monogenic causes including RFC1-related disorders and FGF14-GAA ataxia (SCA27B), a substantial proportion of cases remain idiopathic.
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Heindl et al. (2026) studied this question.
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