Review reveals mechanisms of photodynamic therapy in eliminating cariogenic biofilms and promoting tooth remineralization, highlighting novel targeted strategies for caries management.
Key Points
To elucidate the biological mechanisms by which photodynamic therapy disrupts cariogenic biofilms across various pathological stages and evaluate its potential to induce dental tissue remineralization.
Synthesized evidence on photodynamic therapy mechanisms, biofilm disruption, and hard-tissue repair across different stages of dental caries progression.
Evaluated technical strategies for tuning light parameters and designing targeted photosensitizers to optimize clinical efficacy.
Identified photodynamic therapy as an effective broad-spectrum modality capable of eradicating deep-seated pathogens and circumventing antimicrobial resistance in cariogenic biofilms.
Mapped the mechanistic biological pathways through which photodynamic activation promotes dental tissue remineralization and structural repair.