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September 17, 2026Journal of Clinical MedicineOpen Access

Do Changes in Transtympanic Electrocochleography (TT-ECochG) Reflect the Dynamics of Endolymphatic Hydrops on MRI? Audiological and Radiological Longitudinal Analysis in Patients with Severe Ménière’s Disease After Vestibular Neurectomy—A Pilot Study

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Authors

AJAgnieszka Jasińska-NowackaEWEmilia WnukIPIzabela Pobożny

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Overview

Pilot longitudinal study observes that electrocochleography changes do not parallel MRI endolymphatic hydrops after vestibular neurectomy, suggesting divergent functional and anatomical recovery.

Key Points

  • To evaluate long-term changes in transtympanic electrocochleography (TT-ECochG) after vestibular neurectomy in Ménière’s disease and investigate their correlation with endolymphatic hydrops on MRI and hearing outcomes.
  • Conducted a pilot study in 5 patients with unilateral Ménière’s disease eligible from a cohort of 20 patients who underwent middle fossa vestibular neurectomy.
  • Evaluated patients preoperatively and 2 years postoperatively using audiological assessments, TT-ECochG, and delayed gadolinium-enhanced MRI to assess endolymphatic hydrops.
  • All 5 patients achieved complete control of vertigo, while hearing deterioration of ≥10 dB occurred in 40% (n=2/5).
  • Cochlear endolymphatic hydrops was unchanged in all 5 patients, whereas vestibular hydrops decreased postoperatively in 40% (n=2/5).
  • Postoperative TT-ECochG SP/AP amplitude or area ratios decreased in 40% (n=2/5), increased in 40% (n=2/5), and were absent in 1 patient, showing that electrophysiological changes did not parallel MRI findings.

Cite This Study

Jasińska-Nowacka et al. (2026) studied this question.

synapsesocial.com/papers/6aabb69c5f706d05830e5354https://doi.org/10.3390/jcm15187164
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Dynamics of endolymphatic hydrops according to magnetic resonance imaging of the inner ear after drainage of the endolymphatic sac2025
  2. 2Hydrops regression after vestibular denervation - longitudinal magnetic resonance study in patients with severe Meniere’s disease treated with vestibular neurectomy2024
  3. 3Regression of Endolymphatic Hydrops in Patient With Meniere’s Disease Treated With Vestibular Neurectomy: A Case Report2024
  4. 4Magnetic Resonance Imaging of the Endolymphatic Duct in Patients With Meniere’s Disease: Correlation With Endolymphatic Hydrops Severity and Clinical Findings2026
  5. 5Association between endolymphatic hydrops severity and audio-vestibular outcomes in Ménière’s disease: A systematic review and meta-analysis of correlation coefficients2026