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September 17, 2026Journal of Drug Delivery and TherapeuticsOpen Access

Baraṣ (Vitiligo) in Historical and Unani Literature: A Comprehensive Review

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Authors

MTMohd TariqueNNNaila NaazMZMohammad Zubair

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Overview

Review synthesizes classical Unani concepts and contemporary pathophysiology in vitiligo, suggesting integrated pathways combining traditional regimens with modern dermatology.

Key Points

  • To comprehensively review historical and Unani medical literature on Baraṣ (vitiligo) and evaluate how classical humoral theories align with modern pathophysiology and integrated treatments.
  • Synthesized historical descriptions of Baraṣ across classical Unani, Ayurvedic, and Greco-Roman texts.
  • Mapped traditional concepts (such as Fasād al-Dam and Balghami Ghalīẓ) and prognostic signs against modern autoimmune, neural, genetic, and oxidative stress models.
  • Compared traditional Unani regimental and topical therapies to contemporary interventions, including phototherapy, topical calcineurin inhibitors, corticosteroids, and grafting.
  • Identified significant historical concordance in photomedicine, linking classical psoralen-rich plant applications and sun exposure directly to modern PUVA and narrowband UVB phototherapy.
  • Observed clinical overlaps between ancient Unani subtypes (Baraṣ-i Uẓmā, Baraṣ-i Muntashir) and modern segment-based vitiligo classifications.
  • Highlighted the therapeutic potential of holistic Unani principles (Tanqiya-i Badan, Ta’dili Mizāj) as supportive complements to standard dermatological therapies, pending standardized clinical safety trials.

Cite This Study

Tarique et al. (2026) studied this question.

synapsesocial.com/papers/6aabb6b55f706d05830e53ebhttps://doi.org/10.22270/jddt.v16i9.7961
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