A 75-year-old man presented with left eye fullness, proptosis, and bilateral lacrimal gland enlargement with elevated serum IgG4 levels, initially suggesting IgG4-related disease. However, lacrimal gland biopsy revealed MALT lymphoma. This case highlights the overlapping clinical features of IgG4-related disease and lymphoma and emphasizes the importance of histopathological confirmation before initiating treatment.
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Chang et al. (2026) studied this question.
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