What question did this study set out to answer?

To investigate the quantitative relationship between therapeutic continuous positive airway pressure (CPAP) settings and upper airway collapsibility, measured as pharyngeal opening pressure during drug-induced sleep endoscopy.

September 17, 2026Otolaryngology

The Relationship of Therapeutic Positive Airway Pressure and Upper Airway Collapsibility During Drug‐Induced Sleep Endoscopy

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Authors

JBJulio A. Roque BuenrostroRush University Medical Center KHKatie HollandRush University Medical Center TCT. A. ChapmanRush University Medical Center

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Implication

Retrospective cohort study reveals a positive correlation between therapeutic CPAP and pharyngeal opening pressure in sleep apnea, suggesting CPAP data can estimate airway collapsibility.

Key Points

To investigate the quantitative relationship between therapeutic continuous positive airway pressure (CPAP) settings and upper airway collapsibility, measured as pharyngeal opening pressure during drug-induced sleep endoscopy.
Retrospective cohort study conducted at a single academic teaching hospital evaluating 94 adults with obstructive sleep apnea (AHI ≥ 5) who underwent drug-induced sleep endoscopy with positive airway pressure (DISE-PAP) between 2022 and 2024.
Eligible patients had well-controlled obstructive sleep apnea with an average positive airway pressure adherence exceeding 2 hours per day.
Assessed correlations between median CPAP (mCPAP), 95th percentile CPAP (t95CPAP), and pharyngeal opening pressure (PhOP), along with relationships to body mass index and apnea-hypopnea index.
Mean PhOP was 7.1 ± 2.9 cmH2O, measuring 1.5 cmH2O lower than mCPAP (8.5 ± 2.4 cmH2O) and 3.3 cmH2O lower than t95CPAP (10.3 ± 2.5 cmH2O).
A positive correlation was observed between therapeutic pressures and PhOP, with PhOP increasing by 0.33 cmH2O for each 1-unit increase in mCPAP and by 0.36 cmH2O for each 1-unit increase in t95CPAP.
Each 10-point increase in apnea-hypopnea index was associated with a 0.4 cmH2O increase in mCPAP and a 0.3 cmH2O increase in PhOP, though the correlation between AHI and PhOP was not statistically significant.

Cite This Study

Buenrostro et al. (2026) studied this question.

synapsesocial.com/papers/6aabb8495f706d05830e7f97 https://doi.org/10.1002/ohn.70454

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Implication

Retrospective cohort study reveals a positive correlation between therapeutic CPAP and pharyngeal opening pressure in sleep apnea, suggesting CPAP data can estimate airway collapsibility.

The Relationship of Therapeutic Positive Airway Pressure and Upper Airway Collapsibility During Drug‐Induced Sleep Endoscopy

Discussion

Member takes

Implication

Key Points

Cite This Study

The Relationship of Therapeutic Positive Airway Pressure and Upper Airway Collapsibility During Drug‐Induced Sleep Endoscopy

Discussion

Member takes

Implication

Key Points

Cite This Study

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