Key result
Hybrid coronary revascularization lacks sufficient comparative evidence versus CABG.
Why the study?
Hybrid coronary revascularization (HCR) is an attractive minimally invasive strategy combining durable internal mammary artery grafting with PCI, but only small randomized trials comparing HCR with CABG have recently emerged, raising concerns about its role.
This review provides a perspective on the current state of hybrid coronary revascularization, highlighting the limited evidence base from small RCTs compared to CABG.
Hybrid coronary revascularization (HCR) represents a minimally invasive revascularization strategy in which the durability of the internal mammary artery to the left anterior descending artery graft is combined with percutaneous coronary intervention to treat remaining lesions. It first was introduced in the mid-1990s and aspired to bring together the "best of both worlds" - the excellent patency rates and survival benefits associated with the durable left internal mammary artery graft to the left anterior descending artery alongside the good patency rates of drug-eluting stents, which outlive saphenous vein grafts to non-left anterior descending vessels. Although in theory this is a very attractive revascularization strategy, several years later, only small randomized controlled trials comparing HCR with coronary artery bypass grafting has recently emerged in the medical literature, raising concerns regarding HCR's role. In the current review, we discuss HCR's rationale, the current evidence behind it, its limitations, and procedural challenges.
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Elassal et al. (2021) reported a review. Hybrid coronary revascularization vs. Coronary artery bypass grafting was evaluated. Hybrid coronary revascularization combines internal mammary artery grafting with percutaneous coronary intervention, but evidence comparing it to coronary artery bypass grafting remains limited.
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