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November 22, 2005Journal of Medicinal ChemistryOpen Access

Design, Synthesis, and Action of Oxotremorine-Related Hybrid-Type Allosteric Modulators of Muscarinic Acetylcholine Receptors

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TDTeresa DisingriniMMMathias MuthCDClelia Dallanoce

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Disingrini et al. (2005) studied this question.

synapsesocial.com/papers/6aabc3abc12b6ee7d716e6b0https://doi.org/10.1021/jm050769s
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Therapeutic Opportunities for Muscarinic Receptors in the Central Nervous System2000 · 236 citations
  2. 2Muscarinic Receptor Subtypes1990 · 1,346 citations
  3. 3Allosteric binding sites on muscarinic receptors1997 · 72 citations
  4. 4Systematic Development of High Affinity Bis(ammonio)alkane-type Allosteric Enhancers of Muscarinic Ligand Binding2003 · 30 citations
  5. 5An Improved Synthesis of Oxotremorine1965 · 17 citations