Key result
Lower carotid dicrotic notch values correlate with older age, higher plaque scores, and stroke history.
Cross-Sectional (n=37)
No
The dicrotic notch velocity of the common carotid artery correlates with age, plaque score, peak systolic velocity, and history of stroke or dyslipidemia, suggesting potential as a marker of vascular health.
Should not yet change vascular assessment; hypothesis-generating for dicrotic notch utility in stroke risk evaluation.
The dicrotic notch (DN) is a negative wave that appears just after the peak systolic pressure, and the DN has been reported to reflect closure of the aortic valve and the start of the diastolic phase. However, factors related to the DN of the common carotid artery (CCA) remain unclear. A study involving 37 subjects was conducted to evaluate factors affecting the DN of the carotid artery using carotid ultrasonography. The velocity from the bottom of the DN to the first peak in the diastolic phase was measured. The associations of DN values with sonographic parameters such as peak systolic velocity (PSV) and plaque score (PS) and clinical factors, including age and the presence of hypertension, dyslipidemia, and diabetes mellitus, were assessed. DN values tended to be lower in patients with a stroke history (median 7.3 cm/sec, range 4.2-28.5 cm/sec) than in patients without a stroke history (median 12.4 cm/sec, range 6.0-26.8 cm/sec). Patients with dyslipidemia tended to have decreased DN values compared with those without dyslipidemia. DN values were negatively correlated with age and PS, and were positively correlated with PSV. Further studies are needed to clarify the clinical significance of the DN of the CCA.
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Okabe et al. (2015) conducted a cross-sectional in Stroke or atherosclerotic disease (n=37). Clinical factors (age, plaque score, peak systolic velocity, stroke history) vs. Patients without the respective clinical factors was evaluated on Dicrotic notch (DN) value of the common carotid artery. Dicrotic notch values of the common carotid artery were negatively correlated with age and plaque score, positively correlated with peak systolic velocity, and tended to be lower in patients with a stroke history.
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