Key result
Local resection and radiotherapy show no 2-year recurrence in a mandibular synovial sarcoma case.
Why the study?
Synovial sarcoma is a rare malignant tumor in the oral and maxillofacial regions, particularly in the mandible, with limited reported cases.
Case Report (n=1)
Highlights the importance of immunohistochemical and genetic analysis in diagnosing rare synovial sarcomas of the mandible that may initially mimic osteomyelitis.
Atypical mandibular lesions initially suggesting osteomyelitis may warrant immunohistochemical and genetic analysis; this case extends the differential for rare head and neck sarcomas.
Synovial sarcoma is a rare malignant tumor that occurs in the oral and maxillofacial regions, particularly in the mandible.Herein, we report a rare case of biphasic synovial sarcoma of the mandible in an 82-year-old man.The patient was referred with chronic diffuse painful swelling in the right mandible and underwent local resection of the right mandible.Computed tomography revealed severe destruction of the mandible.An initial biopsy revealed osteomyelitis of the jaw.However, immunohistochemical staining and genetic analysis confirmed synovial sarcoma, and the patient underwent additional resection of the mandible.The histological features are described, and the differential diagnoses are discussed.
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Lee et al. (2024) conducted a case report in Biphasic synovial sarcoma of the mandible (n=1). Local resection and post-operative radiotherapy was evaluated on Recurrence. Local resection followed by post-operative radiotherapy resulted in no evidence of recurrence during a 2-year follow-up in an 81-year-old man with biphasic synovial sarcoma of the mandible.
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