Key result
Synovial sarcoma treatments are linked to ~36% five-year survival, with wide excision identified as preferred.
Why the study?
Synovial sarcoma has a poor five-year survival rate and high local recurrence after local excision, with unclear benefits of other treatments.
Population
34 cases with synovial sarcoma
Comparison
Local excision vs wide excision vs node dissections vs radiation therapy vs Adriamycin
Design
Observational case series
Authors
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Supports wide excision in synovial sarcoma but should not change practice; leaves open Adriamycin role pending prospective trials.
Observational (n=34)
In a series of 34 cases of synovial sarcoma, the 5-year survival rate was 36%, with wide excision identified as the treatment of choice.
Gerner et al. (1975) conducted an observational in Synovial sarcoma (n=34). Various treatments (excision, node dissection, radiation, Adriamycin) was evaluated on Five-year survival. Treatment of synovial sarcoma yielded a 36% five-year survival rate among 34 cases, with wide excision identified as the treatment of choice and Adriamycin showing tumoricidal effects.
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