Why the study?
Women with Turner syndrome have a risk of death from aortic dissection or rupture during pregnancy and postpartum, necessitating updated guidance on pregnancy contraindications.
Pregnancy carries a 2% risk of fatal aortic dissection in women with Turner syndrome, making it a relative contraindication generally and an absolute contraindication if cardiac anomalies are present.
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Supports relative contraindication to pregnancy in Turner syndrome; reinforces Level 1 guideline recommendations for pre-conception aortic assessment.
In women with Turner syndrome, the risk of death from aortic dissection or rupture during pregnancy may be 2%, and this risk persists during the postpartum period owing to pregnancy-related aortic changes. Turner syndrome is a relative contraindication for pregnancy; however, it is an absolute contraindication for pregnancy in a patient with a documented cardiac anomaly. This document replaces the 2008 document of the same name.
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A 2012 study conducted a review in Turner syndrome. Pregnancy was evaluated on Death from aortic dissection or rupture during pregnancy. Pregnancy in women with Turner syndrome is associated with an estimated 2% risk of death from aortic dissection or rupture, which persists during the postpartum period.
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