Intestinal Stricture in Crohn's Disease

This is the authors' abstract. We don't add key points for this paper.

stricture and 10% have had at least one colonic stricture.4 Most of these patients will require at least one surgery during their lifetime.5,6 Even with progress in modern therapies, such as immunosuppressants and biologics which are being used more frequently in treating CD, there is no significant decrease in intestinal complications of CD and the need for surgery.7 The annual incidence of hospitalization is 20% and half of the patients need surgery due to intestinal complications, such as stricture, within 10 years after diagnosis and the risk of postoperative recurrence is 44-55% after 10 years.3,8 Moreover, stricture is one of the major factors for treatment failure or loss of response to biologics in treating CD patients.9 For better management of CD patients, it is very important to know how to diagnose and manage the intestinal stricture during the disease' s course. INCIDENCE AND PREVALENCECurrently, in Asia UC is more common than CD, but with the increasing incidence and prevalence of CD in Asia, it is expected that in the future, CD might be more prevalent than UC, similar to the situation in Western countries.In Western countries, the incidence rates for CD ranges from 14.6 to 17.