Key result
Bipolar epicardial radiofrequency pulmonary vein ablation during off-pump coronary artery bypass resulted in 80% of patients maintaining sinus rhythm at a mean follow-up of 7.6 months.
Why the study?
The safety and applicability of bipolar epicardial radiofrequency pulmonary vein ablation for AF treatment during off-pump coronary artery bypass grafting had not been validated.
Does bipolar epicardial radiofrequency pulmonary vein ablation safely and effectively treat atrial fibrillation in patients undergoing off-pump coronary artery bypass grafting?
Observational (n=15)
Does bipolar epicardial radiofrequency pulmonary vein ablation safely and effectively treat atrial fibrillation in patients undergoing off-pump coronary artery bypass grafting?
Bipolar radiofrequency epicardial pulmonary vein ablation can be safely and effectively performed during off-pump CABG, particularly for patients with intermittent atrial fibrillation.
May support concomitant AF ablation in off-pump CABG; leaves open efficacy and safety pending randomized trials.
OBJECTIVES: : To validate the safety and applicability of a previously unreported innovative technique: bipolar epicardial radiofrequency pulmonary vein ablation for the treatment of atrial fibrillation (AF) in conjunction with off-pump coronary artery bypass surgery. METHODS: : After the completion of off-pump coronary artery bypass grafting (OPCAB) via sternotomy, patients underwent epicardial pulmonary vein ablation using a bipolar radiofrequency clamp placed on the left atrial cuff. The left atrial appendage was removed or excluded in all patients. RESULTS: : Fifteen patients (aged 59-81 years) were treated and reviewed. An average of 2.8 ± 1 grafts were performed per patient; all patients received left internal mammary artery grafts. All sets of pulmonary veins were encircled successfully and ablated. Four patients had additional lesions placed. No patient had pulmonary vein injury. There were no reoperations for bleeding and no mortality. Preoperatively, AF was continuous in 4 patients and intermittent in 11; 10 patients were taking Coumadin preoperatively and 11 were taking antiarrhythmic drugs (AAD). At the follow-up evaluation (7.6 ± 4.4 months; range 1-16 months), 12 patients (80%) are in sinus rhythm (100% in the intermittent AF group, 25% in the continuous AF group); Coumadin has been discontinued in 5 of 10 patients (50% reduction) and AAD have been discontinued in 7 of 11 patients (74% reduction). CONCLUSIONS: : Bipolar radiofrequency epicardial pulmonary vein ablation can be safely and reproducibly used for the treatment of AF in conjunction with OPCAB. Patients with intermittent AF should be strongly considered for adjunctive treatment at the time of OPCAB.
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Wudel et al. (2006) conducted an observational in Atrial fibrillation (n=15). Bipolar epicardial radiofrequency pulmonary vein ablation was evaluated on Sinus rhythm at follow-up. Bipolar epicardial radiofrequency pulmonary vein ablation during off-pump coronary artery bypass resulted in 80% of patients maintaining sinus rhythm at a mean follow-up of 7.6 months.
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