Key result
Aortic valve replacement demonstrates feasibility and good clinical outcomes in ankylosing spondylitis.
Why the study?
The risk and surgical outcomes of aortic valve replacement and ascending aorta replacement in patients with ankylosing spondylitis were not well characterized.
Case Report (n=3)
No
Aortic valve replacement is feasible and yields satisfactory clinical results in patients with severe aortic valve insufficiency associated with ankylosing spondylitis.
Out of 887 consecutive patients who underwent aortic valve replacement between January 1976 and December 1981 at Hannover Medical School Hospital, 3 patients had severe aortic valve insufficiency associated with ankylosing spondylitis (Morbus Bechterew). One of them had huge aneurysmatic dilatation of the ascending aorta and successfully underwent replacement of the ascending aorta by a vascular prosthesis. Microscopical examination of the resected aortic wall showed characteristic findings of aortitis in ankylosing spondylitis. The 3 patients are in good clinical condition at 5 and 6 months, and 2 1/2 years, respectively, after uneventful surgery. It is concluded that aortic valve replacement in patients with ankylosing spondylitis can be performed feasibly and clinical results have been satisfactory. The risk of aneurysmatic dilatation of the ascending aorta resulting from aortitis associated with ankylosing spondylitis is emphasized.
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Kawasuji et al. (1982) conducted a case report in Severe aortic valve insufficiency associated with ankylosing spondylitis (n=3). Aortic valve replacement was evaluated on Clinical condition post-surgery. Aortic valve replacement in 3 patients with ankylosing spondylitis was feasible and resulted in good clinical condition at 5 months to 2.5 years post-surgery.
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