Key result
Multimodal imaging-guided TAVR improves cardiac function in a patient with ankylosing spondylitis and complex valvulopathy.
Why the study?
Complex cardiac damage from ankylosing spondylitis is relatively rare, and previous studies have not proposed effective, minimally invasive surgical treatment options.
Case Report (n=1)
TAVR guided by multimodal imaging may be a feasible and effective minimally invasive treatment option for complex valvulopathy in patients with ankylosing spondylitis.
Suggests multimodal imaging-guided TAVR feasibility in ankylosing spondylitis; hypothesis-generating pending larger studies.
Complex cardiac damage caused by ankylosing spondylitis (AS) is relatively rare in clinical practice. Although the first clear association between AS and aortic regurgitation (AR) was established in 1958, and subsequent case reports have been published, previous studies have not proposed effective, minimally invasive surgical treatment options. This report describes a patient with AS, AR, and mitral regurgitation who experienced frequent premature ventricular contractions, posing an extremely high risk of sudden death. We used a combination of multimodal imaging techniques to perform transcatheter aortic valve replacement on the patient. The patient recovered well after the procedure, with improved cardiac function. This case serves as a reference for treating patients with similar conditions.
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Peng et al. (2025) conducted a case report in Ankylosing spondylitis with complex valvulopathy and ventricular arrhythmias (n=1). Transcatheter aortic valve replacement (TAVR) was evaluated. Transcatheter aortic valve replacement guided by multimodal imaging was successfully performed in a patient with ankylosing spondylitis and complex valvulopathy, improving cardiac function.
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