Key result
Anxiety and depression correlate with COPD outcomes, driven primarily by subjective measures like CAT.
Why the study?
The associations between psychiatric symptoms of anxiety and depression and specific COPD outcomes in patients with stable COPD are uncertain.
Are comorbid anxiety and depression associated with worse clinical and subjective outcomes in patients with stable COPD?
Observational (n=876)
Are comorbid anxiety and depression associated with worse clinical and subjective outcomes in patients with stable COPD?
Effect estimate: 1 - Λ = 0.11
p-value: p=< .001
Psychiatric symptoms of anxiety and depression are significantly associated with subjective COPD outcomes, with a stronger correlation observed in women.
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May support anxiety/depression screening in stable COPD; leaves open whether intervention improves outcomes.
Wu et al. (2022) conducted an observational in stable COPD (n=876). Psychiatric symptoms (anxiety and depression) was evaluated on Relationship between symptoms of anxiety/depression and COPD outcomes sets (CAT, mMRC, number of acute exacerbations and FEV1% predicted) (1 - Λ = 0.11, p=< .001). Psychiatric symptoms of anxiety and depression were significantly associated with COPD outcomes (1 - Λ = 0.11; P < .001), primarily driven by subjective measures like the COPD Assessment Test.
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