Key result
Low diastolic blood pressure levels may be associated with an increased cardiovascular risk, particularly in elderly patients with isolated systolic hypertension, suggesting a J-curve relationship.
Why the study?
The relationship between diastolic blood pressure and cardiovascular risk, including the existence of a J-curve, remains uncertain especially in patients with hypertension and coronary heart disease.
Does excessive lowering of diastolic blood pressure increase the risk of cardiovascular events (J-curve effect) in patients with hypertension and coronary heart disease?
Does excessive lowering of diastolic blood pressure increase the risk of cardiovascular events (J-curve effect) in patients with hypertension and coronary heart disease?
This review highlights a potential J-curve relationship between diastolic blood pressure and coronary events, recommending caution and avoiding strict systolic targets if diastolic blood pressure falls below 65 mm Hg in older patients with coronary heart disease.
No abstract yet. The journal hasn't published one we can show.
No takes yet. Share an insight, caveat, or question.
J Widimský (2006) conducted a review in Hypertension and coronary heart disease. Low diastolic blood pressure vs. Normal or higher diastolic blood pressure was evaluated. Low diastolic blood pressure levels may be associated with an increased cardiovascular risk, particularly in elderly patients with isolated systolic hypertension, suggesting a J-curve relationship.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: