Key result
Achievement of good blood pressure control, irrespective of the initial choice of drug, is the major determinant of outcome in patients with hypertension and diabetes.
Why the study?
Blood pressure control is critical in patients with type 2 diabetes, but the impact of different hypertension outcome trials on management strategies needed synthesis.
Does achievement of good blood pressure control improve outcomes in patients with hypertension and diabetes?
Does achievement of good blood pressure control improve outcomes in patients with hypertension and diabetes?
Good blood pressure control is the primary determinant of outcomes in patients with hypertension and diabetes, often requiring multiple therapies.
The UKPDS highlighted the importance of blood pressure control in patients with type 2 diabetes. In this review I draw on data from the INSIGHT and other recent outcome trials in hypertension which provide clear evidence that it is the achievement of good control of blood pressure, irrespective of the initial choice of drug, that is the major determinant of outcome. The INSIGHT trial provides hard evidence of how resistant to treatment patients with diabetes really are. In this review I offer a theoretical and practical solution in the form of a stepwise algorithm using multiple therapies.
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Morris J. Brown (2003) conducted a review in Hypertension and diabetes. Blood pressure control using a stepwise algorithm with multiple therapies was evaluated. Achievement of good blood pressure control, irrespective of the initial choice of drug, is the major determinant of outcome in patients with hypertension and diabetes.
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