Key result
The 2017 hypertension redefinition increases prevalence to ~69% among people living with HIV.
Why the study?
Hypertension prevalence among people living with HIV (PLWH) is high, but the impact of the 2017 hypertension redefinition on prevalence in this population was not assessed.
Does the 2017 redefinition of hypertension (≥130/80 mm Hg) increase the prevalence of hypertension in people living with HIV compared to the previous standard (≥140/90 mm Hg)?
Cross-Sectional (n=957)
Does the 2017 redefinition of hypertension (≥130/80 mm Hg) increase the prevalence of hypertension in people living with HIV compared to the previous standard (≥140/90 mm Hg)?
Absolute Event Rate: 68.7% vs 47.6%
The 2017 ACC/AHA redefinition of hypertension significantly increases the prevalence of hypertension among people living with HIV, highlighting a critical need for improved blood pressure management in this high-risk population.
May identify more PLWH for CV risk assessment; leaves open whether new thresholds warrant HIV-specific targets or outcome trials.
BACKGROUND: Hypertension is a significant risk factor for cardiovascular disease, a leading cause of death among people living with HIV (PLWH). Studies suggest that hypertension prevalence among PLWH is high, yet none assess how the 2017 redefinition of hypertension as ≥130/80 rather than the previous standard of ≥140/90 mm Hg will affect prevalence among PLWH. This study addresses this gap. METHODS: We examined medical record abstractions of 957 PLWH in Texas from the 2013-2014 Medical Monitoring Project survey. Participants with hypertension were identified by charted diagnosis, antihypertensive medication use, or blood pressure readings ≥140/90 and ≥130/80 mm Hg. Associations with sociodemographic and clinical variables were assessed using Rao-Scott chi-square tests, and odds of having hypertension were calculated using multivariable logistic regression models while adjusting for several demographic and HIV-related variables. RESULTS: The 2017 redefinition of hypertension increased prevalence in the sample by 44.3%, from 47.6% to 68.7%. Age group, body mass index, sex, and race remained significantly associated with hypertension (all P < 0.01). Although prevalence was near equal between males and females at ≥140/90 mm Hg (47.4% and 48.5%, respectively), males were 2.36 times more likely to have hypertension than females (95% confidence interval [CI]: 1.55-3.60) at ≥130/80 mm Hg. Prevalence remained comparable between white (73.3%) and black participants (72.9%). CONCLUSIONS: This study shows that hypertension prevalence is remarkably high among PLWH and is further increased by updated guidelines. Barriers to hypertension control in the HIV care setting should be identified and addressed to facilitate continued improvement in the quality and length of life for PLWH.
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Hyde et al. (2019) conducted a cross-sectional in HIV (n=957). 2017 redefinition of hypertension (≥130/80 mm Hg) vs. Previous standard (≥140/90 mm Hg) was evaluated on Hypertension prevalence. The 2017 redefinition of hypertension (≥130/80 mm Hg) increased hypertension prevalence among people living with HIV from 47.6% to 68.7%.
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