Answers are grounded in this paper and cite their sources.
When DNA replication is slowed down, normally dormant replication origins are activated. Recent work demonstrates that cells adapt by changing the organization of chromatin loops and maintaining the new pattern of origin use in subsequent cell cycles.
No takes yet. Share an insight, caveat, or question.
Blow et al. (2008) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: