Why the study?
Does lobectomy with pulmonary arterioplasty improve outcomes compared to pneumonectomy in patients with centrally located left upper lobe non-small cell lung cancer?
Population
86 patients with centrally located left upper lobe non-small cell lung cancer
Comparison
Lobectomy with pulmonary arterioplasty vs Pneumonectomy
Design
Cohort
Follow-up
5 years
Key result
Lobectomy with pulmonary arterioplasty for left upper lobe non-small cell lung cancer resulted in a 5-year overall survival of 69.5% vs 40.0% for pneumonectomy, with no significant difference.
Authors
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Supports lung-preserving surgery amid modern perioperative therapies; leaves open need for prospective trials on oncologic outcomes.
Observational (n=86)
Yes
Does lobectomy with pulmonary arterioplasty improve outcomes compared to pneumonectomy in patients with centrally located left upper lobe non-small cell lung cancer?
Absolute Event Rate: 69.5% vs 40%
p-value: p=not significant
Lobectomy with pulmonary arterioplasty offers better preservation of respiratory function and fewer complications with comparable survival to pneumonectomy for left upper lobe non-small cell lung cancer.
Yoshikawa et al. (2025) conducted an observational in centrally located left upper lobe non-small cell lung cancer (n=86). Lobectomy with pulmonary arterioplasty vs. Pneumonectomy was evaluated on 5-year overall survival rate (p=not significant). Lobectomy with pulmonary arterioplasty for left upper lobe non-small cell lung cancer resulted in a 5-year overall survival of 69.5% vs 40.0% for pneumonectomy, with no significant difference.