Key result
Catheter ablation for drug-refractory AV nodal reentrant tachycardia resulted in 70% of patients remaining free of arrhythmia without medication or pacemaker over a mean 23-month follow-up.
Why the study?
A catheter ablation technique to treat atrioventricular nodal reentrant tachycardia while preserving anterograde conduction was described and applied in patients with drug-refractory repetitive tachycardia episodes.
Does catheter ablation (fulguration) prevent arrhythmia recurrence in patients with drug-refractory atrioventricular nodal reentrant tachycardia?
Does catheter ablation (fulguration) prevent arrhythmia recurrence in patients with drug-refractory atrioventricular nodal reentrant tachycardia?
Answers are grounded in this paper and cite their sources.
Catheter fulguration effectively treats drug-refractory AV nodal reentrant tachycardia in the majority of patients, though it carries a 10% risk of complete heart block.
This report describes a catheter ablation technique to treat atrioventricular nodal reentrant tachycardia while preserving anterograde conduction, and its application in 42 patients with drug-refractory repetitive episodes of tachycardia. One of these patients had common and reverse forms of tachycardia. Using atrial activation in the His-bundle lead as a reference, the optimal ablation site was selected by positioning an electrode catheter to obtain a synchronous or earlier atrial activation than the reference during tachycardia. At this site, His-bundle deflection was completely absent, or was present at a low amplitude (less than 0.1 mV). In the majority of patients, these criteria were found in the immediate vicinity of the site of proximal His-bundle recording (adjacent to the reference catheter). Shocks of 160 or 240 joules (J) were delivered at this site (mean +/- SD = 518 +/- 392 J/session) with a resulting preferential abolition of impairment of fast retrograde conduction. Anterograde conduction, though modified, was preserved in all patients, except for four (10%) patients who remained in complete heart block. Thirty patients (70%) remained free of arrhythmia without medication or pacemaker for a mean follow-up period of 23 +/- 13 (2-63) months. Six other patients (15%) were controlled with a previously ineffective medication.
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Haı̈ssaguerre et al. (1990) studied Atrioventricular nodal reentrant tachycardia (n=42). Catheter ablation (fulguration) was evaluated on Freedom from arrhythmia without medication or pacemaker. Catheter ablation for drug-refractory AV nodal reentrant tachycardia resulted in 70% of patients remaining free of arrhythmia without medication or pacemaker over a mean 23-month follow-up.
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