Key result
Preoperative anaemia affects ~32% of major surgery patients, driven primarily by iron deficiency.
Cohort (n=2,702)
Yes
Preoperative anaemia is highly prevalent (31.7%) in patients undergoing major surgery, primarily driven by iron deficiency, but with substantial contributions from vitamin B12 and folate deficiencies.
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Supports multifactorial preoperative anaemia assessment beyond iron alone; leaves open optimal management strategies pending trials.
Choorapoikayil et al. (2025) conducted a cohort in Preoperative anaemia (n=2,702). Major surgery was evaluated on Prevalence of anaemia (haemoglobin <120 g/L for women and <130 g/L for men) and its aetiology (95% CI 31.2-32.2). Preoperative anaemia was present in 31.7% (95% CI 31.2-32.2) of patients undergoing major surgery, with iron deficiency being the most common confirmed aetiology (55.2%).
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