Key result
Medical management resolves concomitant COVID-19 acute myocarditis and encephalopathy in a vaccinated patient.
Why the study?
COVID-19 infection can cause severe multisystem complications including myocarditis and encephalitis, with limited reports of simultaneous presentation after vaccination.
Case Report (n=1)
No
This case highlights the possibility of simultaneous COVID-19-induced acute myocarditis and encephalopathy presenting with altered mental status rather than typical cardiac symptoms, even in recently vaccinated individuals.
Clinicians should consider atypical myocarditis-encephalopathy overlap in vaccinated COVID-19 patients; case reports leave open incidence and risk factors.
The ongoing coronavirus disease 2019 (COVID-19) pandemic may result in cardiovascular complications such as myocarditis, while encephalitis is a potentially life-threatening COVID-19-associated central nervous system complication. This case illustrates the possibility of developing severe multisystem symptoms from a COVID-19 infection, despite having received the COVID-19 vaccine within the year. Delay in treatment for myocarditis and encephalopathy can lead to permanent and possibly fatal damage. Our patient, a middle-aged female with a complicated medical history, initially came in without characteristic manifestations of myocarditis such as shortness of breath, chest pain, or arrhythmia, but with an altered mental status. Through further laboratory tests, the patient was diagnosed with myocarditis and encephalopathy, which were resolved within weeks through medical management and physical/occupational therapy. This case presentation describes the first reported case of concomitant COVID-19 myocarditis and encephalitis after receiving a booster dose within the year.
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Saeedullah et al. (2023) conducted a case report in COVID-19-induced acute myocarditis and encephalopathy (n=1). COVID-19 infection was evaluated on Clinical resolution. A 54-year-old female developed concomitant COVID-19-induced acute myocarditis and encephalopathy despite prior vaccination, which resolved within weeks through medical management.
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