Key result
Endomyocardial fibrosis accounts for ~12% of non-hypertensive cardiac diseases at Mulago Hospital.
Why the study?
Endomyocardial fibrosis is a heart disease characterized by fibrosis of the endocardium and subendocardial layers, with limited hemodynamic characterization and comparison to constrictive pericarditis.
Answers are grounded in this paper and cite their sources.
Endomyocardial fibrosis, first described from Uganda by Davies (1948), is a disease of the heart characterized by a fibrosis of the endocardium and subendocardial layers of either the left or right ventricle or both.The fibrosis affects mostly the inflow tracts and the apices of the ventricles, and involvement of the papillary muscles may lead to mitral or tricuspid incompetence.The ventricular outflow tracts are unaffected and the aortic and pulmonary valves are normal.Van der Geld et al. (1966) have demonstrated a predisposition to auto- immune reactivity to the heart in endomyocardial fibrosis.Connor et al. (1967, 1968) have recently published a detailed account of the histopathology of endomyocardial fibrosis in Uganda.From a clinical survey of all cardiac diseases, excluding hypertensive heart disease, at Mulago Hospital, Somers and D'Arbela (1964) found the incidence of endomyocardial fibrosis to be approximately 12 per cent.
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Somers et al. (1968) studied Endomyocardial fibrosis. Endomyocardial fibrosis accounted for approximately 12% of all non-hypertensive cardiac diseases in a clinical survey at Mulago Hospital.
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