Population
Patients with multiple trauma developing Multiple Organ Dysfunction Syndrome (MODS)
Design
Review
Key result
Multiple organ dysfunction syndrome following trauma carries a 50% to 70% mortality rate in surgical intensive care units, requiring early resuscitation and reduction of antigenic load.
Authors
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Supports early resuscitation in high-mortality trauma MODS; leaves open prospective validation of antigenic load reduction strategies.
This review outlines the pathophysiological concepts and therapeutic rationale for managing primary and secondary MODS in multiple trauma patients.
Ertel et al. (1994) conducted a review in Multiple Organ Dysfunction Syndrome (MODS). Therapeutic approaches for MODS was evaluated. Multiple organ dysfunction syndrome following trauma carries a 50% to 70% mortality rate in surgical intensive care units, requiring early resuscitation and reduction of antigenic load.