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September 7, 2026One HealthOpen Access

Exploring the impacts of wildlife trade on zoonotic spillover and disease outbreaks: A multiple-perspective study

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Authors

KWKai WangUniversity of LiverpoolEPEmilio Pagani‐NúñezEdinburgh Napier UniversityZWZiyi WangFirst Affiliated Hospital Zhejiang University

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Overview

Spatiotemporal analysis reveals that wildlife imports elevate disease emergence in countries worldwide, highlighting the critical need for import biosecurity.

Key Points

  • To quantitatively evaluate how international wildlife trade volumes influence the occurrence, frequency, and extreme outbreak events of zoonotic emerging infectious diseases globally.
  • Analyzed country-level annual zoonotic emerging infectious disease data from 1975 to 2013 across global jurisdictions.
  • Implemented a Bayesian zero-inflated negative binomial spatiotemporal model integrated with extreme value theory, adjusting for reporting bias and national surveillance capacity.
  • Wildlife import volume significantly increases the probability of zoonotic emerging infectious disease occurrence and extreme outbreak events, though it shows no significant association with overall outbreak frequency.
  • Wildlife export volume demonstrates no significant relationship with disease occurrence or frequency and exhibits a substantially weaker effect on extreme events.
  • Mammalian species richness and national socioeconomic indicators display complex associations with disease patterns, mediated by the effectiveness of local surveillance systems.

Cite This Study

Wang et al. (2026) studied this question.

synapsesocial.com/papers/6aacaa2429466d65a41ef3bahttps://doi.org/10.1016/j.onehlt.2026.101565
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Zoonotic crossroads: the intersection of wildlife ecology and vector-borne pathogens2026
  2. 2Zoonotic crossroads: the intersection of wildlife ecology and vector-borne pathogens2026
  3. 3Wildlife Trade and Genetic Basis of Disease Susceptibility: A Review2026
  4. 4The anthropogenic fingerprint on emerging infectious diseases2026
  5. 5Targeting Zoonotic Spillover Drivers for Global Pandemic Prevention: A Narrative Review2026 · 1 citations