Key result
Pregnancy after local surgery for recurrent breast angiosarcoma yields term delivery and 5-year disease-free survival.
Why the study?
Primary angiosarcoma of the breast has a poor prognosis and occurs mainly in young women when fertility decreases, making reports of term pregnancies after treatment rare.
Case Report (n=1)
Pregnancy after treatment for primary angiosarcoma of the breast does not appear to negatively interfere with the course of the disease in this case.
Single case suggests pregnancy feasible after recurrent breast angiosarcoma surgery; leaves open generalizability beyond this report.
AIMS AND BACKGROUND: Primary angiosarcoma of the breast is an unusual neoplasm which is generally associated with a dismal prognosis. Given the poor prognosis and the predominance in the third and fourth decades of life when fertility tends to decrease, reports of term pregnancies after treatment of this disease are rare. METHODS AND STUDY DESIGN: We report a case of angiosarcoma of the breast in a 17-year-old patient with a recurrent breast nodule treated by local surgery only. After three years of follow-up without evidence of disease recurrence she became pregnant. RESULTS: A girl weighing 2,430 g was delivered at 38 weeks and two days. The patient has been free of disease for five years now. CONCLUSIONS: Our experience of the present case shows the lack of full information about this tumor. Pregnancy does not seem to interfere negatively with the course of the disease.
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Marana et al. (2000) conducted a case report in Angiosarcoma of the breast (n=1). Pregnancy after local surgery was evaluated on Disease recurrence and pregnancy outcome. Pregnancy following local surgery for recurrent breast angiosarcoma in a 17-year-old resulted in a term delivery and 5 years of disease-free survival.
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