Why the study?
Certain personality traits have been associated with increased risk of chronic systemic inflammation, and sex differences may influence these associations.
Do personality traits associate with systemic inflammation (IL6) differently in healthy men and women?
Cross-Sectional (n=91)
No
Do personality traits associate with systemic inflammation (IL6) differently in healthy men and women?
The personality trait of Openness to Experience is associated with higher systemic inflammation (IL6) specifically in healthy men.
Sex-specific personality-IL-6 associations observed; hypothesis-generating and should not yet change practice or guide interventions.
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FitzGerald et al. (2014) conducted a cross-sectional in Healthy (n=91). Five-Factor Model personality traits was evaluated on Plasma logIL-6 levels (beta 0.38 for Openness in men; beta -0.35 for Agreeableness in women, p=<0.05).
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