Key result
Metastatic renal tumor in the RV wall causes RVOT obstruction years after an ulnar neuropathy.
Why the study?
Cardiac metastases from renal cell carcinoma are rare and usually clinically silent, with limited data on clinical presentation and outcomes.
Case Report (n=1)
Cardiac metastasis from renal cell carcinoma can present as right ventricular outflow obstruction and may be preceded by paraneoplastic neuropathy.
Rare renal tumor metastasis causing RV outflow obstruction warrants consideration in differentials; leaves open link to prior ulnar neuropathy.
Renal cell carcinomas are known to extend into the renal vein and inferior vena cava, but cardiac metastases are rare and usually clinically silent. In the case described here, there was evidence of right ventricular outflow obstruction, associated with a metastatic renal tumour in the right ventricular wall protruding into the ventricular cavity. The patient had presented years earlier with an ulnar neuropathy, for which the tumour may have been responsible. This case highlights the need to consider an underlying paraneoplastic syndrome in a patient presenting with neuropathy, because appropriate investigation could have led to early detection and possible cure of the renal lesion. When renal cell carcinoma is confined to the renal parenchyma, five-year survival is up to 70%, but this falls to 5% in the presence of distant metastases.
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ASH Cheng (2003) conducted a case report in Cardiac metastasis from renal cell carcinoma (n=1). Renal cell carcinoma with cardiac metastasis was evaluated. A metastatic renal tumor in the right ventricular wall caused right ventricular outflow obstruction in a patient who had presented years earlier with an ulnar neuropathy.
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