Key result
Acute pancreatitis acts as a rare trigger for Takotsubo cardiomyopathy mimicking ACS.
Why the study?
Acute pancreatitis as a trigger of Takotsubo cardiomyopathy has been infrequently described and can be misdiagnosed due to overlapping symptoms.
Case Report (n=1)
Takotsubo cardiomyopathy can be a rare complication of acute pancreatitis, and awareness is needed to prevent misdiagnosis as acute coronary syndrome.
Awareness of Takotsubo cardiomyopathy in acute pancreatitis may prevent ACS misdiagnosis; single case leaves open confirmation in larger cohorts.
BACKGROUND: Acute pancreatitis as a trigger of Takotsubo cardiomyopathy has been infrequently described in the literature. Misdiagnosis of this phenomenon can often occur due to overlap in symptomology, particularly in those outside of the usual patient demographic. CASE PRESENTATION: A 27-year-old man with a history of alcohol abuse presented with epigastric and chest pain. Electrocardiography showed ischemic changes, and laboratory workup revealed elevated lipase and troponin. He was diagnosed with acute pancreatitis and managed presumptively as acute coronary syndrome. Subsequent coronary angiography was negative for obstructive coronary artery disease, and left ventriculography demonstrated basal hyperkinesis and apical akinesis, characteristic of Takotsubo cardiomyopathy. CONCLUSIONS: Takotsubo cardiomyopathy is a rare complication of acute pancreatitis. Increased awareness of this phenomenon is required to prevent delays in diagnosis and avoid unnecessary interventions and complications.
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Yeh et al. (2021) conducted a case report in Takotsubo cardiomyopathy complicating acute pancreatitis (n=1). Acute pancreatitis was evaluated. Acute pancreatitis can act as a rare trigger for Takotsubo cardiomyopathy, as demonstrated in a 27-year-old man whose symptoms mimicked acute coronary syndrome.
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