Key result
A postmenopausal woman with acute pancreatitis developed Takotsubo cardiomyopathy and showed persistent systolic dysfunction and apical akinesis at 4-month follow-up despite guideline-directed therapy.
Case Report (n=1)
This case highlights that Takotsubo cardiomyopathy triggered by acute pancreatitis can present with persistent systolic dysfunction and apical akinesis at 4 months, contrary to its typical transient nature.
Recognizing Takotsubo in acute pancreatitis warrants prompt ECG evaluation; extends sparse case reports but leaves causality open.
Takotsubo cardiomyopathy or stress cardiomyopathy is a transient reversible cardiomyopathy characterized by regional wall motion abnormalities that usually extend beyond a single epicardial vascular distribution. It is often precipitated by acute physical or emotional stressors. In this article, we present the case of a postmenopausal woman who was admitted for management of acute pancreatitis. On the second day of admission, she developed shortness of breath and electrocardiographic abnormalities. A transthoracic echocardiogram revealed left ventricular systolic dysfunction and apical akinesis, and coronary angiography revealed normal coronary arteries. She was diagnosed with takotsubo cardiomyopathy triggered by acute pancreatitis and started on guideline-directed heart failure medications. A follow-up echocardiogram 4 months later revealed persistent systolic dysfunction and apical akinesis.
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Abe et al. (2019) conducted a case report in Acute pancreatitis complicated by Takotsubo cardiomyopathy (n=1). Guideline-directed heart failure medications was evaluated on Persistent systolic dysfunction and apical akinesis. A postmenopausal woman with acute pancreatitis developed Takotsubo cardiomyopathy and showed persistent systolic dysfunction and apical akinesis at 4-month follow-up despite guideline-directed therapy.
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