Paraparesis, Urinary Dysfunction, and Acute, Therapy-Resistant Heart Failure in a Previously Healthy Patient Should Not Remain Unexplained

Q: What is the clinical evidence from this study?

Study design: Letter. Population: Heart failure and paraparesis (n=1).

Josef Finsterer; Sounira Mehri

doi:10.1177/23247096261478916

August 1, 2026Journal of Investigative Medicine High Impact Case ReportsOpen Access

Paraparesis, Urinary Dysfunction, and Acute, Therapy-Resistant Heart Failure in a Previously Healthy Patient Should Not Remain Unexplained

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Key result

Letter highlights critical diagnostic gaps, urging viral testing and cardiac MRI in acute heart failure.

n=1

PICO

P

Population

A 61-year-old previously healthy man who developed treatment-resistant heart failure, urinary retention, and lower extremity paraparesis following a mild respiratory infection.

Limitations

No testing for causative infectious agents
Myocarditis and Takotsubo syndrome not adequately ruled out
No MRI of lumbar nerve roots or spine performed
Reference ranges for CSF cell count not provided
No autopsy performed to determine definitive cause of death

Abstract

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Discussion

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Cite This Study

Finsterer et al. (2026) conducted a letter in Heart failure and paraparesis (n=1). This letter highlights diagnostic omissions in a reported case of acute heart failure and paraparesis, emphasizing the need for viral panels, cardiac MRI, and autopsy to identify the true etiology.

synapsesocial.com/papers/6ad115b700741cc3fba7d854 https://doi.org/10.1177/23247096261478916

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Paraparesis, Urinary Dysfunction, and Acute, Therapy-Resistant Heart Failure in a Previously Healthy Patient Should Not Remain Unexplained

PICO

Limitations

Abstract

Discussion

Cite This Study

Paraparesis, Urinary Dysfunction, and Acute, Therapy-Resistant Heart Failure in a Previously Healthy Patient Should Not Remain Unexplained

PICO

Limitations

Abstract

Discussion

Cite This Study

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Keep reading

More from Journal of Investigative Medicine High Impact Case Reports