Key result
PCI therapy linked to ~110% higher odds of antiplatelet compliance one year after CHD hospitalization.
Why the study?
Compliance with antiplatelet therapy and its affective factors in patients with coronary heart disease one year after hospitalization were analyzed to improve secondary prevention.
What are the rates and affective factors of antiplatelet therapy compliance in patients with coronary heart disease one year after hospitalization?
Observational (n=398)
No
What are the rates and affective factors of antiplatelet therapy compliance in patients with coronary heart disease one year after hospitalization?
One year after hospitalization for first-diagnosed coronary heart disease, 83% of patients maintained good antiplatelet therapy compliance, with age and prior PCI being significant predictors.
Answers are grounded in this paper and cite their sources.
Prior PCI may flag higher-compliance patients post-CHD hospitalization; should not yet change practice and leaves causal mechanisms open in observational data.
Objective To analyze the compliance of antiplatelet therapy and its affective factors in patients with coronary heart disease one year after hospitalization, which will improve the secondary prevention for coronary heart disease. Methods The study enrolled 398 patients (363 patients completed the study) with first-diagnosed coronary heart disease in a provincial hospital in Anhui province from January to December 2012. The therapeutic compliance of these patients, as well as the affective factors, were evaluated with a self-designed questionnaire either through phone revisit or out-patient interview. The factors influencing therapeutic compliance of patients with coronary heart disease were analyzed by Logistic regression analysis. Results The results showed 301 (83%) patients were in a good therapeutic compliance, while the rest of 62 (17%) patients were not. The affective factors included age, ways of medical payment, whether with PCI treatment or not, and the types of coronary heart disease (stable angina, unstable angina and acute myocardial infarction), χ2 values were 9.425, 6.262, 5.556 and 6.895. The main affective factors were the age [OR=0.471(0.284-0.782)] and whether with PCI therapy or not [OR=2.104(1.123-3.942)]. Conclusions Patients had poor compliance of antiplatelet therapy one year after hospitalization, medical staffs should make treatment protocol and nursing measures according to age and whether with PCI treatment or not of patients, so that the belief and behavior of medication can be intensified, the medication compliance can be elevated and the secondary prevention can be well implemented.
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Zhang et al. (2015) conducted an observational in coronary heart disease (n=398). PCI therapy vs. No PCI therapy was evaluated on Good therapeutic compliance (OR 2.104, 95% CI 1.123-3.942). PCI therapy was significantly associated with better antiplatelet therapy compliance one year after hospitalization for coronary heart disease (OR 2.104; 95% CI 1.123-3.942).
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