Key result
MMP-7 A-181G and C-153T promoter polymorphisms show no association with bladder cancer risk.
Why the study?
The role of MMP-7 genotypes in bladder cancer risk has been seldom examined among patients, particularly in Taiwan.
Are MMP-7 genotypes A-181G and C-153T associated with bladder cancer risk in a Taiwanese population?
Comparison
MMP-7 genotypes A-181G and C-153T vs healthy controls
Design
Case-control study
Authors
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No association in this Taiwanese case-control study; leaves open MMP-7 polymorphism relevance to bladder cancer in other populations.
Case-Control (n=750)
Are MMP-7 genotypes A-181G and C-153T associated with bladder cancer risk in a Taiwanese population?
p-value: p=0.5475
MMP-7 promoter polymorphisms A-181G and C-153T do not appear to influence susceptibility to bladder cancer in the Taiwanese population.
LIAO et al. (2018) conducted a case-control in Bladder cancer (n=750). MMP-7 A-181G and C-153T genotypes vs. Healthy controls was evaluated on Bladder cancer risk (p=0.5475). MMP-7 A-181G and C-153T promoter polymorphisms were not significantly associated with bladder cancer risk in a Taiwanese population (p for trend=0.5475).
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