Patin (Pangasianodon hypophthalmus) Fish Protein Concentrate Improves Albumin and Immunity Levels in Malnutrition Rats

Background and Objective: Malnutrition has become a health problem in developing countries such as Indonesia.This can provide an effect on body composition, decreasing albumin levels and immunity status.Patin fish is well-known to have a high level of protein concentration and has a positive-effect on malnutrition.To investigate the effect of Patin fish protein concentrate (PFPC) on the albumin levels and immunity status of Sprague Dawley baby ratʼs malnutrition.Materials and Methods: The study was a true-experiment study with a randomized pre-posttest with a control group.Thirty rats were divided into 5 groups; control of normal (K 1 ) and malnutrition (K 2 ), malnutrition with PFPC 13.26 (P 1 ), 19.89 (P 2 ) and casein 13.26 (P 3 ) mg gG 1 b.wt.dayG 1 .The analysis was carried out with the paired t-test, Wilcoxon, ANOVA and Kruskal Wallis test.Results: The results showed that malnutrition has an effect on BW, albumin levels, leukocytes count and IgG levels.Post-intervention showed an increase of albumin levels in the intervention groups (p<0.05) and a significant decrease in control groups (p<0.05).There is a decrease in leukocytes count and IgG level post-intervention in intervention groups (p<0.05) and a significant increase in the post-intervention control groups (p<0.05).There were significant differences between all groups on albumin levels, leukocytes count and IgG levels.Conclusion: PFPC could improve albumin and immunity levels in malnutrition baby rats.PFPC dose of 19.89 mg gG 1 b.wt.dayG 1 is the best formula in improving albumin and immunity levels.