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Glioneuronal tumors are rare and mostly consist of gangliogliomas. These tumors are usually benign and total resection is usually curative. We report on a new type of tumor in an adolescent with first onset of epilepsy. MRI showed a small contrast-enhancing lesion with minimal perilesional edema. The radiological diagnosis was compatible with ganglioglioma. Awake surgery was performed and total resection could be achieved. The diagnosis of glioneuronal tumor with PATZ1 gene fusion was made. This recently described tumor entity has not yet been included in the WHO classification of tumors of the central nervous system (fifth edition, 2021).
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Landers et al. (2025) studied this question.
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