“On water” synthesis of dibenzo-[1,4]-diazepin-1-ones using l -proline as an organocatalyst and under catalyst-free conditions, and their evaluation as α-glucosidase inhibitors

Functionalized dibenzo-[1,4]-diazepin-1-ones are synthesized using the “on-water” concept in the presence of l -proline (organocatalyst; 20 mol%) and under catalyst free conditions (sealed tube) in an aqueous medium.