Synthetic routes to o -carboxyphenyl derivatives of pyrimidine, required for testing as potential plant growth regulators, are described. 2-(4-Phenylpyrimidin-2-yl)benzoic acid (3), 2-(2-phenylpyrimidin- 4-yl)benzoic acid (4) and 2-(2-phenylpyrimidin-5-yl)benzoic acid (5) were prepared by utilizing amide-acid chloride intermediates in the generation of the pyrimidine ring in each instance.
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Harris et al. (1979) studied this question.
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