Key result
Caudal anesthesia lowers postoperative cortisol and prolactin levels vs general anesthesia alone in children.
Why the study?
The effects of caudal anaesthesia on plasma cortisol and prolactin concentrations during the early postoperative period in children were not well established.
Does caudal anaesthesia with 0.25% bupivacaine reduce postoperative plasma cortisol and prolactin concentrations in children undergoing lower abdominal and genitourinary surgery?
Population
60 children ASA 1.8 month to 10 yrs undergoing lower abdominal and genitourinary surgery
Comparison
Caudal anaesthetics with 0.25% bupivacaine plus general anaesthetic vs standardized general anaesthetic alone
Design
Randomized controlled study
Follow-up
1 hour after surgery
Authors
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Caudal anesthesia addition attenuates early stress response in children; supports routine consideration for lower abdominal and genitourinary procedures.
RCT (n=60)
Does caudal anaesthesia with 0.25% bupivacaine reduce postoperative plasma cortisol and prolactin concentrations in children undergoing lower abdominal and genitourinary surgery?
Caudal anaesthesia with bupivacaine effectively attenuates the stress hormone response to postoperative pain in children undergoing lower abdominal and genitourinary surgery.
Solak et al. (2000) conducted an RCT in Lower abdominal and genitourinary surgery (n=60). Caudal anaesthesia vs. Standardized general anaesthetic was evaluated on Plasma cortisol and prolactin concentrations at 1 hour postoperatively. Caudal anaesthesia significantly attenuated plasma cortisol and prolactin concentrations at 1 hour postoperatively compared to general anaesthesia alone in children.
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