Key result
Wingspan stent simulation suggests high radial stress and structural deformation contribute to perforator occlusion.
Why the study?
Perforator infarction after intracranial Wingspan stent placement is a critical problem with unclear mechanisms.
Computational simulation suggests that structural deformation and biomechanical stress from Wingspan stenting may contribute to the mechanism of perforator occlusion.
Perforator infarction represents a critical problem after intracranial Wingspan stent. To explore the mechanism of perforator infarction, we simulated the stent-artery interaction at an atheromatous plaque with perforator. Structural deformation and biomechanical stress distribution after stenting were analyzed. High radial stress values were located along the stent struts, which surrounded the area with high circumferential stress. Stretched perforator orifice in a circumferential direction after stenting was simulated. These results show that structural deformation could play a role in the mechanism of perforator occlusion after Wingspan stenting.
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Fujimoto et al. (2013) studied Perforator infarction after intracranial stenting. Wingspan stent was evaluated on Structural deformation and biomechanical stress distribution. Simulation of the Wingspan stent-artery interaction demonstrated high radial stress and circumferential stretching of the perforator orifice, suggesting structural deformation contributes to occlusion.
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