Key result
Admission blood glucose, not antecedent diabetes, is linked to ~5% higher 1-year mortality after AMI.
Why the study?
The relative association of admission blood glucose levels and antecedent diabetes on early and long-term survival after myocardial infarction was unclear.
Is admission blood glucose concentration a more powerful predictor of mortality after myocardial infarction than an established diabetes diagnosis?
Population
4111 consecutive patients admitted with acute myocardial infarction in the UK
Comparison
Admission blood glucose concentration vs antecedent diabetes diagnosis
Design
Retrospective cohort study
Follow-up
1 year
Authors
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May enhance post-MI risk stratification via admission glucose beyond diabetes history; leaves open whether targeting it improves outcomes.
Cohort (n=4,111)
No
Is admission blood glucose concentration a more powerful predictor of mortality after myocardial infarction than an established diabetes diagnosis?
Hazard Ratio: 1.05 (95% CI 1.03–1.08)
Admission blood glucose is a stronger independent predictor of short- and long-term mortality after acute myocardial infarction than an established diagnosis of diabetes.
Gholap et al. (2012) conducted a cohort in Acute myocardial infarction (STEMI and NSTEMI) (n=4,111). Admission blood glucose concentration vs. Antecedent diabetes diagnosis was evaluated on All-cause mortality at 30 days and 1 year (HR 1.05, 95% CI 1.03-1.08). Admission blood glucose concentration was independently associated with 1-year mortality after acute myocardial infarction (HR 1.05; 95% CI 1.03-1.08), whereas antecedent diabetes was not.
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