Key result
Late second-trimester fetal heart rate decelerations are linked to ~62% greater PROM risk.
Why the study?
Electronic fetal heart rate monitoring characteristics in pregnancies with preterm delivery before 32 weeks of gestation using late second-trimester nonstress test were unclear.
Does the presence of second-trimester decelerations predict premature rupture of membranes in pregnancies with preterm delivery before 32 weeks?
Population
100 singleton infants born before 32 weeks of gestation with second-trimester EFM records
Comparison
Pregnancies with second-trimester decelerations vs without second-trimester decelerations
Design
Observational cohort study
Authors
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Should not yet change monitoring protocols; hypothesis-generating for decelerations predicting PROM in very preterm deliveries.
Observational (n=100)
Does the presence of second-trimester decelerations predict premature rupture of membranes in pregnancies with preterm delivery before 32 weeks?
Absolute Event Rate: 60% vs 37.1%
p-value: p=< 0.05
Periodic or episodic decelerations during late second-trimester fetal monitoring are associated with an increased risk of premature rupture of membranes in preterm deliveries.
Yanagihara et al. (2001) conducted an observational in Preterm delivery before 32 weeks of gestation (n=100). Second-trimester fetal heart rate decelerations vs. No second-trimester decelerations was evaluated on Premature rupture of the membranes (PROM) (p=< 0.05). Periodic or episodic fetal heart rate decelerations during late second-trimester monitoring were associated with an increased risk of premature rupture of membranes (60.0% vs 37.1%; p<0.05).
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