Key result
Multimodal analgesia, regional anesthesia, gabapentinoids, and subanesthetic ketamine help prevent chronic postoperative pain.
Why the study?
Chronic postoperative pain affects every fifth patient after elective or emergency surgery, with unclear mechanisms and prevention strategies.
Chronic postoperative pain affects approximately 20% of surgical patients, highlighting the importance of preventive strategies such as multimodal analgesia, regional anesthesia, and specific pharmacological agents like gabapentinoids and ketamine.
The overview is devoted to the problem of chronic postoperative pain. At the moment every fifth patient undergone elective or emergency surgery suffers from chronic postoperative pain. The paper presents current data on epidemiology of chronic pain syndrome following different operations, as well as diagnostic criteria and pathophysiological mechanisms of transformation of acute postoperative pain into chronic pain syndrome. Risk factors responsible of formation of chronic postoperative pain are described in details, among which the most valuable are presence of pain before surgery, trauma of the surgery, intensity of pain in early postoperative period. The article discusses modern methods of prophylaxis of chronic postoperative pain. The most perspective drugs for preventive action include gabapentinoids and ketamine in subanesthetic doses. The main role in prophylaxis belongs to regional anesthesia and analgesia. The role of multimodal approach to perioperative analgesia is presented in the work as well.
No takes yet. Share an insight, caveat, or question.
А. М. Овечкин (2016) conducted a review in Chronic postoperative pain. Multimodal perioperative analgesia was evaluated. Chronic postoperative pain affects approximately 20% of surgical patients, with prevention relying on multimodal analgesia, regional anesthesia, gabapentinoids, and subanesthetic ketamine.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: