Malabsorption and Jejunitis in American Peace Corps Volunteers in Pakistan

Article1 December 1966Malabsorption and Jejunitis in American Peace Corps Volunteers in PakistanJOHN LINDENBAUM, M.D., THOMAS H. KENT, M.D., HELMUTH SPRINZ, M.D., F.A.C.P.JOHN LINDENBAUM, M.D., THOMAS H. KENT, M.D., HELMUTH SPRINZ, M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-65-6-1201 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTropical sprue, a syndrome of unknown cause characterized by diarrhea, weight loss, malabsorption, and changes in small intestinal morphology, occurs in both native residents and visitors to tropical countries. The syndrome has been frequently described in European and American military personnel stationed in Asia (1, 2) or Puerto Rico (3, 4). During the past year, two cases of severe symptomatic sprue have been observed in Peace Corps Volunteers in East Pakistan, and several cases have been seen among Volunteers in Venezuela (5).Recent studies from Thailand, India, Pakistan, Puerto Rico, and Haiti have shown a high prevalence of malabsorption and...References1. KEELEBOUND KDJP: Sprue in India. Brit. Med. J. 1: 77, 1946. CrossrefMedlineGoogle Scholar2. STEFANINI M: Clinical features and pathogenesis of tropical sprue. Medicine (Balt.) 27: 379, 1948. CrossrefMedlineGoogle Scholar3. GARDNER FH: A malabsorption syndrome in military personnel in Puerto Rico. Arch. Intern. Med. (Chicago) 98: 44, 1956. CrossrefGoogle Scholar4. SHEEHYCOHENWALLACELEGTERS TWWCDKLJ: Tropical sprue in North Americans. JAMA 194: 1069, 1965. CrossrefMedlineGoogle Scholar5. SMITH R: Personal communication. Google Scholar6. SPRINZSRIBHIBHADHGANGAROSABENYAJATIKUNDELHALSTEAD HREJCDS: Biopsy of small bowel of Thai people. 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Author, Article, and Disclosure InformationAffiliations: Dacca, East Pakistan, and Washington, D. C.From the Pakistan-SEATO Cholera Research Laboratory, Dacca, East Pakistan, and the Walter Reed Army Institute of Research, Washington, D. C.This work was supported in part by research agreement 196802 between the National Institutes of Health, Bethesda, Md., and the Pakistan-SEATO Cholera Research Laboratory.Requests for reprints should be addressed to John Lindenbaum, M.D., First Medical Division, Bellevue Hospital, 462 First Ave., New York, N. Y. 10016. 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Studies in Peace Corps VolunteersJOHN LINDENBAUM, M.D., CHARLES D. GERSON, M.D., THOMAS H. KENT, M.D.Attempts to modify the intestinal villus architecture in miceRegarding the Definition of Tropical SprueTRANSIENT (REVERSIBLE) MALABSORPTION OF VITAMIN B 12Jejunal morphology of the African in UgandaThe villus architecture of the small intestine in the tropics: A necropsy studyTropical sprue.Current Views on Tropical Sprue and a Comparison to Nontropical SprueDigestive Disease as a National ProblemTropical Sprue—Specific Disease or Extreme of a Spectrum?ARTHUR B. FRENCH, M.D., F.A.C.P.Tropical SprueCorrelation of Jejunal Function and Morphology in Patients with Acute and Chronic Diarrhea in East Pakistan 1 December 1966Volume 65, Issue 6Page: 1201-1209KeywordsArmed forcesCholeraDiarrheaEnteritisResearch laboratoriesWeight loss Issue Published: 1 December 1966 PDF downloadLoading ...